
Last week's number one, Click, starring Adam Sandler and Kate Beckinsale, was pushed to third place, while Martin Scorsese's return to the world of gangsters in The Departed, with Leonardo di Caprio and Jack Nicholson, entered at second.
Prada took £3.27 million, according to Screen International, while Scorsese's The Departed made £2.30 million on its opening weekend.
Another new entry - Accepted at eight - sees a team of enterprising student pals open their own university after failing to secure places elsewhere.
The top ten in full:
1. (-) The Devil Wears Prada - £3.27m
2. (-) The Departed - £2.30m
3. (1) Click - £1.28m
4. (2) Hoodwinked - £0.91m
5. (3) World Trade Centre - £0.87m
6. (5) The Queen - £0.51m
7. (4) Children of Men - £0.46m
8. (-) Accepted £0.35m
9. (7) Little Miss Sunshine £0.17m
10. (6) Talladega Nights: The Ballad of Ricky Bobby - £0.10m








