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Quinlan (Gilly Roach) is said to have called time on the romance because of Keegan's kisses with co-star Jack P Shepherd (David Platt) on the soap.
Shepherd recently split from long-term girlfriend Lauren Sheppey, 19, and rumours are now rife that his on-screen chemistry with Keegan (Tina McIntyre) has spilled over into real life.
A source told The Mirror: "Everyone had noticed the chemistry between Jack and Michelle on set. They've become really close recently, but they aren't diving into anything too serious just yet.
"They have been out to Relish and a few pubs around Manchester, but they have been careful not to be photographed together and want to keep it low-key. Lauren's barely moved her stuff out of her house with Jack and he doesn't want to hurt her."
Shepherd previously admitted that Lauren had hated watching him kiss Keegan on the ITV1 show.
The split is the latest in a rash of break-ups among the Coronation Street cast. Kym Ryder (Michelle Connor) last week announced her separation from husband Jack, while the newspaper reports that Ryan Thomas (Jason Grimshaw) and Tina O'Brien (Sarah Platt) have also ended their relationship.
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