The Home and Away actress, whose character Leah suffered from agoraphobia after being caught up in racist riots last year, said that depression is no longer a "taboo subject" thanks to the coverage it gets on television.
Nicodemou's husband Chrys Xipolitas also sought treatment at a Sydney rehab clinic earlier this year while battling depression.
She told TV Week magazine: "I think everyone knows someone who has experienced depression and it isn't a taboo subject anymore.
"It was nice that the show dealt with it and agoraphobia because it isn't something that's always spoken about."
She also said that while filming those storylines, she found it "hard to go home at the end of the day and be happy".