Speaking on an upcoming episode of India's Most Desirable, the actor revealed his choice to host Simi Garewal.
Deol said: "The most gorgeous woman in the industry today? There are a lot. If I had to go with one I would go for Anushka.
"She's spontaneous, she's spunky. I have only met her once. I have seen her work, I think she's very talented and when I met her she came across as someone quite down to earth... and talkative.
"She talks a lot but I think it suits her and just makes her that much more of a better person."
Sharma reportedly shares an on-off relationship with her Band Baaja Baraat co-star Ranveer Singh.
Deol also speaks about his relationship with Preeti Desai and admits to earlier drug use in the programme, which has yet to air.
India's Most Desirable screens on Star World, Sunday at 9pm (IST).