The actor made his debut in the sex thriller opposite Mallika Sherawat, who plays a married woman who falls in love with Hashmi's character.
He told the Mumbai Mirror: "I was nobody when Murder clicked. Actually, I never wanted to be an actor. I might have gotten into special effects for all you know.
"However, if and when one tastes success, he wants to succeed all the time. It happened to me after Murder. Importantly, I understood what the film business is all about. It was the sex in Murder that sold.
"There was an entire conservative section of society that shunned Murder."
However, the actor admitted that he was embarrassed by his performance in the breakthrough film.
Hashmi said: "I still cringe when I see my performance in Murder. I faltered. I fumbled. Mahesh Bhatt told me to draw my emotions from real instances. 'Don't fake it', he ordered. 'Develop your own individuality', he thundered.
"Ever since, his advice is firmly entrenched in memory. Yet, Murder will always hold a special place in my heart."
The Jism star said this week he wants to return to making risky films again.
Despite this, he has decided to appear in his first U-rated film so his children can see him on the big screen for the first time.