The event is part of Vanity Fair's annual, week-long celebration leading up to the Academy Awards and the 14th instalment of 'Campaign Hollywood', with proceeds going to a campaign for the education of girls around the world through film and social media advocacy.
Pinto's spokesperson confirmed the news in a statement, saying: "When Vanity Fair approached Freida to co-host the pre-Oscar party with them she was more than happy to align with Vanity Fair and bring attention to the 10X10 Girl Rising initiative.
"She has always felt committed to this cause and wouldn't miss out on this opportunity."
Called 'DJ Night with Freida Pinto and Vanity Fair', the event - which attracts the biggest stars of Hollywood - will feature a special performance by DJ AcE.
The Desert Dancer star will be the first Indian actress to have hosted the Vanity Fair pre-Oscar party. The event also marks the 100th anniversary of the magazine.
Pinto is the global ambassador for Plan International's 'Because I Am a Girl' campaign focusing on the plight of the girl child.
The 85th Academy Awards takes place on February 24 at the Dolby Theatre in Los Angeles.
Photo Gallery: The nominees for the 85th Academy Awards in pictures:
Copyright: PA Images Chris Pizzello / AP