Adams, who is credited with helping to shape the modern image of the Dark Knight, will return to the character this summer.
The 12-issue miniseries sees Batman face a series of challenges from villains and allies old and new. As the battles grow more intense, the Caped Crusader discovers an over-arching force behind the events.
"I have been collecting bits and pieces of Batman's life and time over the years since I was doing Batman regularly," Adams said. "With even this massive series, I haven't been able to shove them all in, but the juiciest and richest morsels are there. Have comic books always been this much fun?"
Batman: Odyssey will debut in July.