Co-written by Walter Fernandez Jr and Arastao Maree, the book includes input from the actor, who will oversee the creative process and make changes he deems necessary.
The storyline sees the former Batman star embark on a dimension-spanning adventure that draws from his real-life career as well as fictitious sources.
"I never in a thousand years dreamed they'd do any kind of comic book about me," West told MTV. "That's what I wanted: something that was more Walter Mitty or Pink Panther, with adventure the kids will love, and action.
"For example, an adventure might be based on him meeting Batman and how he feels about it... He might even be meeting himself as Mayor West on Family Guy, and laughing at it or along with it."
He added: "There are so many ways to go, as you know - especially with the audience today. I have this incredibly wonderful fanbase out there, and I know they'll love this."
Featuring interior art by Lipe and covers by Matt Bellisle, The Mis-Adventures Of Adam West debuts in Spring 2011.