The comic will continue as a part of the main DC Comics imprint.
Concern was voiced by fans over the potential fate of the title following the forthcoming closure of its current home, DC's WildStorm imprint.
"There was always a home for it," Busiek told Newsarama. "The question was, how are things going to be organised at DC? And would it be a home where we wanted to stay? The answer is, yes, absolutely.
"The trouble at the beginning was that they couldn't give us any details right away. As soon as they announced that WildStorm was closing, it's not like my editor could have told me ahead of time, because he heard about it that day, when they made the announcement.
"So at the time, I was being contacted by other publishers who were asking if Astro City is available. And the answer [was], 'I don't know. Maybe?' I talked to them, and made it clear that DC is busy with internal stuff right now, but they're going to give me some information, and after that, we'll be able to make a decision."
Busiek said that he and artist Brent Anderson are continuing to work on the book and there should be no gap in production during its change of imprints.