At the Emerald City Comicon, Davis explained that his decision to leave was mostly due to a desire to spend more time on creator-owned projects.
"One of the main reasons I felt it was time to leave the B.P.R.D. ongoing series was just the fact that at the end of the day, there was only so much comic work I could fit in and I kept having to push my own Marquis book further and further back," Davis explained to CBR.
"I've drawn more issues of B.P.R.D. than any other comic series I've worked on. It wasn't a quick decision, but one I had been thinking about for a while," he added.
Davis has served as the regular artist on the ongoing series since the third volume, B.P.R.D.: Plague of Frogs, back in 2004.
Tyler Crook will take over as the book's new artist once Davis finishes his run after the conclusion of B.P.R.D.: Hell on Earth: Gods.