According to USA Today, the superhero team's new lineup will comprise 14 members, including mainstays Superman, Batman, Wonder Woman, Flash, Green Lantern and Aquaman.
"The approach is very much about who they are behind the masks and how they interact together and how these personalities mix," DC co-publisher Geoff Johns told the newspaper.
"With the world's greatest superheroes, how does that team actually work? Do they all get along? Being able to pull together and see how that relationship is forged and continues to grow has to be at the heart of that book."
Promo artwork for the new series previously revealed that unlikely candidate Cyborg will feature as one of the comic's main characters, in place of Martian Manhunter.
"He's a character I really see as the modern-day, 21st-century superhero," Johns added. "He represents all of us in a lot of ways. If we have a cellphone and we're texting on it, we are a cyborg - that's what a cyborg is, using technology as an extension of ourselves."
Earlier today, DC confirmed that all of its core titles will relaunch following the 'Flashpoint' event. The rebooted series will include reworked origin stories and redesigned costumes by artist Jim Lee.
Justice League #1 arrives in stores on August 31.
> Read our complete 'Flashpoint' coverage