The publisher has licensed the property from current owners Condé Nast.
John Cassaday, Alex Ross, Ryan Sook and Jae Lee have been named as cover artists. Dynamite promised that the unannounced creative team "will bring justice to The Shadow".
The hero began life on a radio show in 1930 before spawning pulp magazines stories, comics, computer games and movies, including the 1994 film starring Alec Baldwin.
Kyle Baker, Andy Helfer and Howard Chaykin produced several acclaimed series for DC Comics in the '80s. Dark Horse Comics and Eternity have since published The Shadow, but a new comic has not been released for some years.
"We are pleased and excited to entrust The Shadow to the capable, creative hands of Dynamite Entertainment," said Jerry Birenz, licensing attorney for Condé Nast.
"We look forward to a continuation of the long tradition of The Shadow in comic books, and the enjoying of the new adventures and experiences Dynamite Entertainment will bring us."
Dynamite is known for its licensed properties, including A Game of Thrones, Zorro and Bionic Man.