Kiss Kiss Bang Bang follows the adventures of a British spy codenamed 'Charles Kiss', with each new bearer of the name surgically altered to look like the original. The series follows the latest agent Alan McGrath and his struggle to survive the grim fate awaiting him.
"I think fans of the original book will appreciate and find familiar some of the overall feel or atmosphere of the book - the action, the intense situations that the characters find themselves in," Milligan told Newsarama.
"The characters are different from the original book but operate in a similar world. They probably belong to the same clubs.
"When we first meet him, Alan McGrath is an idealist. He believes in Western freedom and he believes that MI6 and the other intelligence organisations do a fine job trying to protect it. Most of all he believes in Charles Kiss, the spy who achieved legendary, heroic status.
"Everything is at stake for Alan McGrath. His life, of course, but even more than that. Everything he believes in. The woman he loves. The man he hero worships. And perhaps, the very Western freedom that he joined MI6 to protect."
Mike Perkins and Tony Bedard's original title was published in 2004.
Peter Milligan is also working on Red Lanterns and Justice League Dark as part of DC Comics' 52 title relaunch.