Marvel Entertainment's chief creative officer will make his first appearance at a UK convention in May.
The Mark Millar-helmed event will also feature an audience with Warren Ellis and a panel featuring comedians Jimmy Carr and Frankie Boyle discussing their role in Millar's magazine CLiNT.
Other newly confirmed guests include Olivier Coipel, Charlie Adlard, Paul Grist, Mike Carey, Glenn Fabry, Sean Phillips and Eric Stephenson.
> Kapow! Comic Con returns for second year
> Kapow! Comic Con 2012 tickets go on sale
The inaugural London Super Comic Convention is also due to be held at London's ExCel centre on February 25 and 26, with special appearances from Stan Lee and IDW Publishing.
Kapow! Comic Con will be held on May 19 and 20 at the London Business Design Centre in Islington.
Tickets - which are only available in advance - start at £20 for day passes, with weekend passes priced at £35.