Writer Brian Wood and artist Ming Doyle will team on the six-issue miniseries.
The story focuses on Mara Prince, a celebrity athlete in a sports-obsessed future.
Her career is put at risk when she begins to manifest superpowers during a high-profile volleyball game.
"I decided to create this during the post-DC 52 reaction regarding women in comics, female characters in superhero stories and their depiction within, and all that discussion that followed," Wood told Comics Alliance.
"In addition to just feeling like I had a powerful, relevant story to tell, I wanted to prove, if only to myself, that a story like this can be told without reducing it to or otherwise relying on these sorts of base depictions of women.
"Like Channel Zero, Jennie One, Supermarket, Demo, Local, The New York Four, The New York Five, DV8, and a good deal of Northlanders, Mara features a complex, realistic, multi-faceted female lead."
The series was one of the projects announced at Image Expo in Oakland, California, last week, alongside Grant Morrison's Image debut Happy!, Phonogram: The Immaterial Girl, Nick Spencer's Bedlam and two projects by Steve Niles.
Wood is currently working on Conan and The Massive for Dark Horse Comics.
His acclaimed Demo miniseries similarly dealt with superpowered people in a host of different situations.