The comics publication will relaunch with issue #2.1 that month, debuting four new strips.
Millar's own Supercrooks and The Secret Service will begin their serialisation, alongside Monty Nero and Mike Dowling's Death Sentence, and Frankie Boyle's Rex Royd.
"With brand new strips and a great new look, this fresh new look at the CLiNT format is perfect for new, old and lapsed readers alike. If you gave it a miss first time around, you've been missing out," read a statement from publisher Titan.
"It's a fab, meaty package and one of the most thrilling, high-value concentrations of comics around. The exclusive news and interviews are just the icing on a particularly delectable, beefy cake. And yes, I'm mixing my mains with my dessert, but I don't care. It's that bloody good."
Titan also announced that Kick-Ass spinoff Hit Girl will debut in CLiNT 2.2 in June.
CLiNT 2.1 will be available on May 9 in the US, and May 10 in the UK.
Watch an advertisement for CLiNT magazine below: