The cartoonist teased his future work, which will follow the conclusion of his Vertigo title Sweet Tooth.
"I definitely have plans for more creator-owned books," Lemire told Comic Book Resources.
"I have three different projects that I am working on at various stages. I pretty much know which one will be next but beyond that I can't discuss any specifics. This is by no means the end of me drawing or writing creator-owned projects."
Lemire currently writes DC Comics' Animal Man and is in the process of transitioning from Frankenstein: Agent of S.H.A.D.E. to Justice League Dark.
He made a name for himself on creator-owned titles including the Essex County Trilogy.
Sweet Tooth, which he writes and illustrates, will draw to a conclusion with December's issue #40.