The 1,068-page book collects the second eight volumes of Robert Kirkman's popular horror series, spanning issues #49 to #96.
Released under the publisher's Skybound imprint, Walking Dead: Compendium Two features a new cover illustration by series artists Charlie Adlard and Cliff Rathburn.
"It's just such a big, huge book that really offers a lot of bang for your buck," Kirkman told USA Today. "The idea of having Volume 1 and 2 sitting next to each other on a reinforced shelf really excites me.
"I'm thrilled that we finally have enough issues released to be able to produce Volume 2. Now I'm looking forward to four years of 'When does Volume 3 come out?'"
The Walking Dead, which spawned a hit TV show on AMC, reaches the milestone of 100 issues later this month.
The Walking Dead Compendium Two will be available on October 3, priced at $59.99 (£38.63).