It will unveil the project at the Amazing Spider-Man panel at San Diego Comic-Con International at 12.30pm on Sunday, July 15.
It will launch in October, and while no other details have been revealed it is assumed to involve Spider-Man's foe Carnage.
The villain famously starred in the 1993 crossover 'Maximum Carnage' which ran across the entire Spider-Man line.
The character was last seen in the Carnage USA miniseries.
Details of the heavily teased return of Punisher War Zone will also be announced during the panel.