The 200-page hardcover volume collects issues #1 through #8 of the 1994 series, along with bonus material.
Bloodshot creators Kevin VanHook and Don Perlin have contributed an original short to accompany the existing material, and artist Barry Windsor-Smith has produced a cover design.
The first eight issues of the comic served as the character's introduction into the original VH1 Valiant Universe.
Valiant relaunched its shared universe earlier this year with the launch of titles based around the popular characters Harbinger, X-O Manowar and the aforementioned Bloodshot.
Sony Pictures acquired the screen rights to Bloodshot in March, but is yet to officially green light a movie based on the property.
Valiant Masters: Bloodshot Vol. 1 - Blood of the Machine is released on October 24.