The graphic novel will mark the beginning of a multimedia project from the publisher and DeZerlin Media.
Launching in summer 2013, it will be joined by books, games and other merchandise in the run-up to the release of a movie.
Dragon Resurrection follows the adventures of two scientist brothers who create an army of dragons from a sample of ancient DNA to protect their discovery from a rogue US general.
"It's fast, it's fun, it's cool - we purposely made a book that we ourselves wanted to read," said writer/producer Mark Byers.
"We're so happy to be part of the Dark Horse team and to have them share our enthusiasm for the franchise."
The publisher claims that the Chang brothers are "the first-ever Chinese superheroes to be seen in the mainstream international markets".