The villain will make his first full appearance since DC Comics' New 52 relaunch last September.
When a fan tweeted at Snyder asking if Edward Nigma would return, he responded with a simple "yes".
"I will use the Riddler in 2013," the writer clarified in a follow-up tweet.
The character was glimpsed on the cover and in the opening pages of Batman #1 but otherwise has not featured in any of the franchise's 12 tie-in books since the relaunch.
Snyder is also preparing for the return of the Joker, who disappeared in Detective Comics #1, apparently leaving his face behind.
Snyder also writes Swamp Thing for DC and American Vampire for the publisher's Vertigo imprint.
He will be collaborating with James Tynion IV on the 'Night of the Owls' spinoff Talon from September.