The legendary creator's project began as an essay tribute to his friend and mentor Steve Moore (no relation).
Unearthing will be released in hardcover, softcover and a limited edition format.
"An intensely poetic and innovative work of biography, Unearthing maps the lifetime of author, orientalist and occultist Steve Moore, while simultaneously investigating the extraordinary history of South London with which that life has been intertwined," said Top Shelf.
"Integrating text with haunting and exquisite imagery, Unearthing excavates a territory at the margins of a city, of reality, and of human imagination."
It was also previously adapted into a spoken word piece with a soundtrack by Faith No More.
Moore collaborated with photographer Mitch Jenkins on Unearthing, which will be available to order in October's edition of Previews. The signed limited edition will be available separately from December.
Top Shelf also publishes Moore and Kevin O'Neill's League of Extraordinary Gentlemen.