Mark Waid and Leinil Francis Yu have been confirmed as the creative team on the new Marvel NOW! title.
The team was previously teased with the word "Indestructible".
"Honestly, it's a lot like my experience with Fantastic Four - I never thought I'd want to write this book until it was offered and I began thinking about it," Waid told Comic Book Resources.
"So many great writers, so many landmark moments - it was intimidating, still is. But the more I began to think about the relationship between Bruce and Hulk, the more I began fantasising about what it would be like to take the core concept a little more 'back to centre' like we did with Daredevil, the more intrigued I became.
"The reception to our approach on Daredevil had a lot to do with how I'm coming at Hulk - assuming that everything we know about Hulk is still true, everything he's been through - but, as we did with Daredevil, having Banner turn a corner and deciding to take a whole new, less 'woe is me', view of his condition."
Waid recently celebrated 25 years in the comic book industry.
Indestructible Hulk will debut in November.