The recently announced conclusion of his run on Winter Soldier will see the end of his collaboration with the publisher for the foreseeable future.
"To end all speculation: Cap #19 and Winter Soldier #14 are my last Marvel books for now," he wrote on Twitter.
"But I may return, because Marvel has been my home."
Brubaker revealed in June that he would be ending his run on Captain America to focus on creator-owned work.
His critically acclaimed stint on the title began in 2005 and will shortly conclude prior to the Marvel NOW! creative shake-up.
The writer is currently working with frequent collaborator Sean Phillips on Fatale at Image Comics.