The publisher has teamed up with Susan G. Komen for the Cure for the initiative and will release titles bearing the charity's logo and prominent pink hues throughout the month.
"It's rewarding to see the partnership between Marvel and Susan G. Komen For The Cure produce such exciting art to raise awareness about the risk of breast cancer to both women and men," said Marvel publisher and president Dan Buckley.
"We hope that all our fans take a moment this month to educate themselves on the ways to fight - and reduce - this risk of this disease by checking out the free resources Komen has to offer."
Titles including Fantastic Four, Captain Marvel, Thor and The Invincible Iron Man will all be included in the month-long promotion.
Avengers #31, which is released on October 10, will be the first title to receive a Susan G. Komen For The Cure variant cover.