The new Marvel NOW! title will apparently feature someone other than Peter Parker donning the iconic suit.
"Peter Parker has spent a lifetime living up to the responsibilities his powers foisted upon him but his Amazing story finally ends dramatically in the historic Spider-Man #700," said the publisher.
"NOW! the new Spider-Man has arrived and he is better in every single way. Smarter, stronger… Superior."
Dan Slott will write the previously teased title with artist Ryan Stegman.
Stegman promised a costume redesign that would add "aggressiveness" to the character's appearance in an interview with USA Today.
"He's not going to be doing things the old Spider-Man way," added Slott. "There will be a new way of doing things.
"The first story arc is called 'Hero or menace?' I think that pretty much tells you where we're going."
Superior Spider-Man #1 will debut in January.