East of West and Feel Better Now were unveiled at New York Comic Con and will debut in spring 2013.
Reuniting with FF artist Nick Dragotta in April, East of West centres around a mission which sees the Four Horsemen of the Apocalypse trying to kill the president of the United States.
March will see the launch of Feel Better Now, which heralds Hickman's return to comics illustration.
It centres around a group psychiatrists who begin to play with the lives of their patients, and the consequences of their games.
Feel Better Now was previously solicited as a one-shot, but will now be published as a full original graphic novel.
Hickman is currently writing The Manhattan Projects as an ongoing series at Image.