Artist Dustin Nguyen will return to his fan-favourite property with frequent collaborating writer Derek Fridolfs.
The series will begin with the Halloween-themed story 'The Calendar of Small Events' and continue on Wednesdays with Thanksgiving, Christmas and New Years tales.
"This has been a passion project of mine for some time now, and for anyone that's followed my work, I'm sure it's more of an 'it's about time'," Nguyen told DC's The Source.
"The look and style is a slight departure from my usual (think the exact opposite of serious), but the idea has always been the same - to take our favourite existing Gotham characters, place them in fun scenarios without having to be tied to just one continuity or look and feel. It's basically a Batman book for fans, by two huge fans."
"At times in various platforms, Batman has been extremely dark and taken very seriously," added Fridolfs.
"So respectfully, we're going in the opposite direction and having a bit of whimsical fun with a whole city of characters beloved by fans and especially ourselves. Li'l size… big enjoyment."
Li'l Gotham previously ran as a series of backups in DC's 2009 annuals.