The single issues will be available to download from the Kindle Store, iBookstore and NOOK Store for Amazon, Apple and Barnes & Noble products.
"As e-readers and tablets continue to explode in popularity it's important for us to offer consumers convenience and choice in how they download digital comics and graphic novels and these new distribution deals with the top three e-bookstores do just that," said Jim Lee, co-publisher at DC Entertainment.
"We're very excited to work with Amazon, Apple and Barnes & Noble to bring bestselling DC Comics and Vertigo periodicals to their e-bookstores."
DC is the first comics publisher to make its titles available on these three platforms.
Digital editions of its graphic novels were previously being sold from the three stores.