The tribute to '80s action movies will shoot in mid-December near his studio in Chatham County, North Carolina.
"I'm working hard to develop more of my own film and animation projects, which will enable me to keep more of my work close to home and utilise many untapped local talents and businesses," he told Discover Chatham.
"Vandroid is hopefully the first of many live-action film projects I'll be bringing to Chatham County."
Edwards is best known as the artist of comics including Jonathan Ross's Turf, Marvel 1985 and The Question.
He has also worked on concept, design and illustrations for film projects including Batman Begins, Star Wars and Harry Potter.
Vandroid will be supported by a soundtrack and comic book.