The comic book - which was made into a film in 2005 - will be performed as part of Manchester's Midwinter LassFest in January.
"V for Vendetta takes us back into unfamiliar territories, this time in a brand new fringe adaptation of Alan Moore's classic 1980's comic strip from the team that brought you the Ballad of Halo Jones in January," said the organisers. "It's London, but not as we know it.
"A shadowy freedom fighter known only as 'V' uses terrorist tactics to fight against his totalitarian society. Adapted by Sean Mason (Hot Fat, The Ballad of Halo Jones, Porridge), the Lass is delighted to premiere this important and prescient tale of a struggle against oppression in the surveillance society."
Performances will be held on January 8-10 and 27.
The Wachowskis' adaptation of the David Lloyd-illustrated series starred Hugo Weaving and Natalie Portman.
Masks inspired by the comic were recently banned in Dubai.
An stage adaptation of Guillermo del Toro's Pan's Labyrinth has also been announced this week.