Writer Donny Cates and comedian Eliot Rahal are teaming up on the new project, which will debut in Dark Horse Comics' anthology.
"Hunter Quaid is a drunken, misanthropic, time-travelling detective from the forties, but that's not all," said the publisher.
"As we follow Hunter on his journeys, we find that not all is as it seems, and sharp-eyed readers will find hidden clues to the book's needlessly elaborate, totally awesome secret."
"Donny and I love comics - they have the amazing ability to embody positivity, and that's really what Hunter is about," said Rahal.
"We were just two desperately alone, and drunk, strangers who became best friends that wanted to write a funny, real, and inspiring character.
"Hunter is a labour of love and would be nothing without the uncanny conceptual art of Melissa Curtin, and the deadly colour work of Lauren Affe. We are all so honoured and thrilled for Hunter to have found his first home at Dark Horse Presents."
Hunter Quaid will debut in Dark Horse Presents #24 on May 22.