The industry's leading distributor will no longer offer titles such as Essential X-Men and Astonishing Spider-Man for April due to low demand, Bleeding Cool reports.
Marvel UK is predominantly a newsagent brand collecting issues from several of the publisher's popular series in a single issue for a fraction of the price of their combined cost.
Other titles released under the banner include Mighty World of Marvel, Wolverine and Deadpool, Incredible Hulk, Avengers Assemble and Marvel Legends.
Retailers will still be able to order these titles through magazine distributors, but their circulation in Britain is likely to significantly shrink.
Marvel's parent company Disney issued an edict ruling in 2011 stating that all original superhero content must be produced in the US.