Grant - who played Daphne Millbrook in Heroes - is collaborating with her brother on We Will Bury You for IDW Publishing.
The series will feature art by Kyle Strahm and covers by 30 Days of Night's Ben Templesmith.
"Growing up in a small town, [Zane and I] got really close because we didn't know that many people who were into the music and books we were into," Grant told MTV News. "So, it's logical to me that we would work together.
"We have a similar sense of the world, sense of humour and work ethic, so it just really works out."
The siblings will be focusing on life in the early 20th century as much as they will the hordes of flesh-eating undead.
"We wanted to include worldviews of the time, slang and even jobs that you might not hear about in a normal history class," said Grant.
"It may sound lame, but there's no reason you can't learn while reading a comic."
We Will Bury You will debut in early 2010.