The broadcaster has set aside a £4.5m fund to support new console and PC games which incorporate educational elements.
As a result of this investment, Time Gentlemen, Please! studio Zombie Cow is now developing PC game Privates. Aimed primarily at young males, the game will take a light hearted approach to advice on sexually transmitted infections and teenage pregnancy.
Speaking at a briefing today, Channel 4 Education commissioning editor Matt Locke revealed that Privates will be a "spoof on the Space Marine genre", in which players enter a young man's privates to shoot down infections.
Available as a free PC download in March 2010, the game could also launch on the Xbox Live Indie Games channel at some point in the future.
Read our review of Time Gentlemen, Please! here.