Speculation that Activision is planning a new edition of the music title featuring the band arose after the studio released a survey to gauge interest in the concept.
"Celebrate the entirety of the Red Hot Chili Peppers' life, starting with their early days in LA, to their famous Hyde Park concert to their highly anticipated new studio album," read notes from the survey.
"Discover the story behind their legendary music as you unlock interviews, retrospectives, concert footage and other commentary."
The Red Hot Chili Peppers' music has previously appeared in Guitar Hero III and Guitar Hero: On Tour. The band's Blood Sugar Sex Magik album also appeared as a full download in rival series Rock Band.
Activision is yet to confirm the development of a Red Hot Chili Peppers edition of Guitar Hero.