Tracks from Nas, P Diddy, Public Enemy, Wiley as well as producers Danja and Nitti Beats will be available in the hip-hop music game.
Over 40 tracks will be included on launch, allowing players to rap, sing and upload videos of their performances online.
The game will be released on November 5 for Xbox 360 and PlayStation 3.
The additions in full:
P Diddy (Featuring The Notorious B.I.G., Lil’ Kim & The Lox: 'It’s All About The Benjamins (Remix)'
Method Man (Featuring Mary J. Blige): 'You’re All I Need/I’ll Be There For You'
Nas (Featuring Diddy): 'Hate Me Now'
Nelly: 'Hot In Herre'
Public Enemy: 'Fight The Power'
Nitti Beats: 'Hand’s Up'