DMC will be a reboot of the franchise and follows Dante on a revenge mission in a modern day setting.
As well as a story with a darker tone, the series' signature sword and gun gameplay will feature new weapons and powers.
The title will be developed by Ninja Theory, which has worked on Heavenly Sword and upcoming adventure title Enslaved: Odyssey To The West.
Rumours that the British studio was working on the franchise surfaced earlier this year, while a "Western" DMC game was discussed by Capcom earlier this month.
The last title in the hack-and-slash series was Devil May Cry 4 in 2008.
Image copyright: Capcom