In addition to being voted 'Best Of Show', 2K's upcoming FPS was also voted 'Best Original Game', 'Best PC Game' and 'Best Action/Adventure Game'.
Sony's PlayStation Vita trumped the Wii U to pick up the award for 'Best Hardware', while The Elder Scrolls V: Skyrim was voted 'Best Console Game' and 'Best Role Playing Game'.
Batman: Arkham City, which was voted Game Of E3 2011 by Digital Spy readers, failed to pick up any awards, despite being nominated three times.
> Read our Best Of E3 feature here
The winners in full:
Best Of Show: BioShock Infinite (Irrational Games/2K Games for PC, PS3, Xbox 360)
Best Original Game: BioShock Infinite (Irrational Games/2K Games for PC, PS3, Xbox 360)
Best Console Game: The Elder Scrolls V: Skyrim (Bethesda Game Studios/Bethesda for PS3, Xbox 360)
Best Handheld Game: Sound Shapes (Queasy Games/SCEA for PSVita)
Best PC Game: BioShock Infinite (Irrational Games/2K Games for PC, PS3, Xbox 360)
Best Hardware: PlayStation Vita (Sony Computer Entertainment)
Best Action Game: Battlefield 3 (DICE/EA Games for PC)
Best Action/Adventure Game: BioShock Infinite (Irrational Games/2K Games for PC, PS3, Xbox 360)
Best Role Playing Game: The Elder Scrolls V: Skyrim (Bethesda Game Studios/Bethesda for PC, PS3, Xbox 360)
Best Fighting Game: Street Fighter X Tekken (Capcom/Capcom for PS3, Xbox 360, PSVita)
Best Racing Game: Forza 4 (Turn 10 Studios/Microsoft Studios for Xbox 360)
Best Sports Game: FIFA Soccer 12 (EA Canada/EA Sports for PC, PS3, Xbox 360)
Best Strategy Game: From Dust (Ubisoft Montpellier/Ubisoft for PC, PS3, Xbox 360)
Best Social/Casual Game: Sound Shapes (Queasy Games/SCEA for PSVita)
Best Motion Simulation Game: The Legend of Zelda: Skyward Sword (Nintendo EAD/Nintendo for Wii)
Best Online Multiplayer: Battlefield 3 (DICE/EA Games for PC, PS3, Xbox 360)
Best Downloadable Game: Bastion (Supergiant Games/WB Games for PC, Xbox 360)
