Its closest challengers are Uncharted 3: Drake's Deception and Elder Scrolls V: Skyrim in second and third respectively.
At the tail-end of the chart, Goldeneye: Reloaded climbs six places to re-enter at ten, below Saints Row: The Third and Need For Speed: The Run.
The top ten in full:
1. (1) Call of Duty: Modern Warfare 3 (Activision)
2. (4) Uncharted 3: Drake's Deception (Sony)
3. (6) Elder Scrolls V: Skyrim (Bethesda Softworks)
4. (3) FIFA 12 (Electronic Arts)
5. (2) Assassin's Creed: Revelations (Ubisoft)
6. (5) Battlefield 3 (Electronic Arts)
7. (8) Need for Speed: The Run (Electronic Arts)
8. (7) Saints Row: The Third (THQ)
9. (9) Batman: Arkham City (Warner Bros Interactive)
10. (16) Goldeneye: Reloaded (Activision)
Leisure software charts compiled by Chart Track, (C) 2011 UKIE Ltd.
Watch the Modern Warfare 3 live-action trailer below: