The Xbox 360 platform holder confirmed that the Activision shooter attracted the most players to its online service, followed by Call of Duty: Modern Warfare 2 and 3, Halo Reach and Battlefield 3.
Xbox Live Arcade's best-selling game was Pinball FX 2, followed by Full House Poker, Castle Crashers and Fruit Ninja Kinect.
Microsoft also revealed the top sellers on its Games for Windows Live service, confirming that Age of Empires Online, GTA IV, Batman: Arkham City and Super Street Fighter IV Arcade Edition led the way on the PC storefront.
Angry Birds was named as the most popular game on the Windows Phone store, followed by Fruit Ninja and Plants vs Zombies.
A complete rundown of the charts is available on Major Nelson's blog.
Watch a trailer for Call of Duty: Black Ops below: