The video is the first English language footage shown of the game, featuring both animated story and gameplay footage.
In the game, players control Oliver, a 13-year-old boy who is transported to a fantasy world as he embarks on a quest to revive his deceased mother.
The PlayStation 3 RPG is a collaboration between famed animation studio Studio Ghibli and Professor Layton creators Level-5.
Publisher Namco Bandai has also pushed back the North American release date from early 2012 to match the European date set for early 2013.
Ni No Kuni: Wrath of the White Witch will be available exclusively on PlayStation 3.
Watch the Japanese Ni No Kuni announcement trailer below: