The two-day PC and indie expo will take place on July 6 and 7 at the Brighton Centre. Tickets cost £12 for one day or £20 for the full two.
Rezzed features developer sessions, tournaments and hands-on time with upcoming PC and indie games, as well as retro arcades and market stalls selling hardware and merchandise.
Aliens: Colonial Marines will be on show at the event, as well as Sega's Leftfield Collection of indie games, which are curated by the editors of Eurogamer and PC site Rock, Paper, Shotgun.
Total War developer Creative Assembly will be in attendence, as well as The Indie Stone of Project Zomboid fame.
Eurogamer managing director Rupert Loman said of the event: "Following last year's hugely successful fourth Eurogamer Expo, we're broadening our horizons for 2012 by introducing a new summer event to highlight the best of PC and indie games.
"PC and indie games are enjoying huge success now after years in the ascendancy and we want to draw more attention to that fact and give people the opportunity to get up close to the biggest names and games before they're released."
Eurogamer Expo 2012, meanwhile, takes place at London's Earls Court from September 27 to 30.
Last year's event broke attendance records, welcoming upwards of 34,000 people, compared to 20,00 the previous year.
Star Wars: The Old Republic's worldwide release date, OnLive's UK launch and the first European hands-on with Elder Scrolls V: Skyrim were some of the exclusives at the expo.
Photo gallery - view screenshots from Aliens: Colonial Marines, on show at this year's Rezzed event: