Announced during EA's E3 press conference, the news confirms earlier rumours that the game will ditch competitive multiplayer in favour of co-op.
It was also revealed that the game would release in February 2013.
Dead Space 3 will take place on a frozen planet and features a new character named John Carver.
A graphic novel teaser appeared on the official Dead Space website last week, revealing that it is "the start of John Carver's saga in the Dead Space Universe".
Dead Space 3, the sequel to Visceral Games' survival horror third-person shooter Dead Space 2, will launch within the next financial year, EA confirmed earlier this month.
Watch the Dead Space graphic novel teaser below: