It is followed by a slew of new entries in second, third and fourth, the highest of which is The Amazing Spider-Man, followed by Spec Ops: The Line and London 2012: The Game.
With the release of the Dawnguard DLC, Elder Scrolls V: Skyrim climbs one place to seven, sandwiched between former number one releases Future Soldier at six and Max Payne 3 at eight.
The PlayStation Vita release of Metal Gear Solid HD Collection, meanwhile, sees Konami's iconic franchise re-enter the chart at ten, above fellow collection and new entry The Ratchet & Clank Trilogy.
The top ten in full:
1. (1) LEGO Batman 2: DC Super Heroes (Warner Bros. Interactive)
2. (-) The Amazing Spider-Man (Activision)
3. (-) Spec Ops: The Line (2K Games)
4. (-) London 2012: The Game (Sega)
5. (2) FIFA 12 (Electronic Arts)
6. (3) Ghost Recon: Future Soldier (Ubisoft)
7. (8) Elder Scrolls V: Skyrim (Bethesda Softworks)
8. (4) Max Payne 3 (Rockstar)
9. (5) Battlefield 3 (Electronic Arts)
10. (-) Metal Gear Solid HD Collection (Konami)
11. (-) Ratchet & Clank Trilogy (Sony)
12. (7) Mario & Sonic at the London 2012 Olympic Games (Sega)
13. (9) Sniper Elite V2 (505 Games)
14. (10) FIFA Street (Electronic Arts)
15. (-) Mass Effect 3 (Electronic Arts)
16. (12) Batman: Arkham City (Warner Bros. Interactive)
17. (19) Assassin's Creed Revelations (Ubisoft)
18. (17) Call Of Duty: Black Ops (Activision)
19. (6) Lollipop Chainsaw (Warner Bros. Interactive)
20. (18) Skylanders Spyro's Adventure (Activision)
Leisure software charts compiled by Chart Track, (C) 2012 UKIE Ltd.
Watch a trailer for LEGO Batman 2: DC Super Heroes below: