Rockstar's upcoming sequel featured in a promotional video for the event, leading to speculation that it would be on show.
The footage has since been removed from the trailer, with a gamescom spokesperson telling CVG that it was included in error.
"Rockstar Games is not scheduled and has never been scheduled to exhibit at gamescom 2012," explained event communications manager Franko Fischer.
"We apologise for any confusion this may have caused," he added, before promising spectacular exclusives for the event.
"Although GTA 5 won't be at the show, I think we will once again have the most spectacular world premieres set for the events."
Announced last year, Grand Theft Auto 5 takes place in the city of Los Santos and its surrounding hills, countryside and beaches. Its lead character is thought to be a man named Albert De Silva, played by Ned Luke.
Grand Theft Auto 5 has been tipped for an October release, following a leaked developer CV. The game has been predicted to sell 14 million copies when it launches.
Despite the rumours, Rockstar North has remained tight-lipped, promising more details in the coming weeks and months.
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Watch the Grand Theft Auto V announcement trailer below: