The publisher, which is currently the largest supporter of Wii U with seven announced titles, told investors that development of Wii U games is relatively cost effective for the studio's budget.
"Out of seven games we are planning to launch, five games are ports, so those are games for which there is a quite small reinvestment to do," he said.
"The two games that are original are ZombiU of course and Rayman, so those ones of course are more expensive. But we are not talking about games today, like we were spending on Ghost Recon or Assassin's Creed, so they are much smaller of cost.
"For the other five games you are talking about a small budget, I'd say of less than a million euro to make some of the ports, I'd estimate. So together I don't think we have a huge investment on the Wii U."
In this case, the low financial investment for developing Wii U titles allows the company to make a large content investment for the new system.
Guillemot added: "As we've always said, when there is such an innovation the need is not to have big production value but to concentrate on the innovation, this is what we are trying on Rayman and ZombiU."
Ubisoft recently expressed that it feels "penalised" by the lack of new hardware, which may be stifling game creativity.
Nintendo believes that the success of Wii U will be determined by its price rather than its hardware specs, though the company still has not announced what the system's price will be.
The Wii U is scheduled to launch this holiday season. Ubisoft has hinted that Wii U may launch in November, which agrees with a recent Wii U game release date. Reports have also indicated a possible December launch for the system.
Watch the announcement trailer for ZombiU below: