The poll - which was run to coincide with the London 2012 Olympics starting today (July 27) - saw EA's sporting franchise crowned the winner.
It was followed by competing franchise Pro Evolution Soccer and Wii launch title Wii Sports.
Tiger Woods PGA Tour, Track & Field and Virtua Tennis also ranked highly in the poll.
Outside of the top ten, cult classic QWOP was voted higher than Mario Tennis, NBA Live and UFC Undisputed.
Digital Spy readers' top ten sports game franchises:
2=. Pro Evolution Soccer
2=. Wii Sports
4. Tiger Woods PGA Tour
5=. Track & Field
5=. Virtua Tennis
7. Madden NFL
8. Top Spin
9. Kinect Sports
10. Mario & Sonic
The next edition, FIFA 13, will be available on Xbox 360, PS3, PC, Wii, 3DS, Vita, PS2, iPhone and iPad from September 28.
> 'FIFA 13' preview: EA's latest football game offers a touch of class
Watch the Kinect trailer for FIFA 13 below: