Celebrating its fourth week on top, Sega's Olympic tie-in is followed by LEGO Batman 2 and Batman: Arkham City, two games riding high on the back of Christopher Nolan's Dark Knight Rises release.
At the tail end of the chart, Tiger Woods PGA Tour 13 re-enters after a lengthy absence, charting below FIFA 13.
The top ten in full:
1. (1) London 2012: The Game (Sega)
2. (4) LEGO Batman 2: DC Super Heroes (Warner Bros Interactive)
3. (6) Batman: Arkham City (Warner Bros Interactive)
4. (3) The Amazing Spider-Man (Activision)
5. (5) Modern Warfare 3 (Activision)
6. (2) Ghost Recon: Future Soldier (Ubisoft)
7. (8) Elder Scrolls V: Skyrim (Bethesda Softworks)
8. (7) Max Payne 3 (Rockstar)
9. (9) FIFA 12 (Electronic Arts)
10. (12) Tiger Woods PGA Tour 13 (Electronic Arts)
Leisure software charts compiled by Chart Track, (C) 2012 UKIE Ltd.
Watch a trailer for London 2012: The Official Video Game below: